John Wiley & Sons Inc

Architectural Drawing is the classic, comprehensive compendium of architectural drawing. Featuring examples from many high-profile architects and firms, the nearly one-thousand drawings and photos in this book illustrate all of the various types and methods of architectural drawing.

Making a psychiatric diagnosis in children can be challenging: some clinicians say the incidence of some childhood disorders, such as bipolar disorder and ADHD, is over-diagnosed while others say they are undiagnosed, undertreated, and are a large burden on society. The drug treatment of child psychiatric disorders can also be controversial in children and adolescents. Clinical Child Psychiatry fills the need for an objective, clinically relevant source to dispel this confusion.

The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. "Bench to Bedside": A key strength of this book that sets it apart from general cancer biology references is the interweaving of all aspects of cancer biology from the causes, development and diagnosis through to the treatment and care of cancer patients -- essential for providing a broader view of cancer and its impact. The highly readable presentation of a complex field, written by an international panel of researchers, specialists and practitioners, would provide an excellent text for graduate and undergraduate courses in the biology of cancer, medical students and qualified practitioners in the field preparing for higher exams, and for researchers and teachers in the field. For the teaching of cancer biology, special features have been included to facilitate this use: bullet points at the beginning of each chapter explaining key concepts and controversial areas; each chapter builds on concepts learned in previous chapters, with a list of key outstanding questions remaining in the field, suggestions for further reading, and questions for student review. All chapters contain text boxes that provide additional and relevant information. Key highlights are listed below: * An overview of the cancer cell and important new concepts. * Selected human cancers: lung, breast, colorectal, prostate, renal, skin, cervix, and hematological malignancies. * Key cellular processes in cancer biology including (a) traditionally important areas such as cell cycle control, growth regulation, oncogenes and tumour suppressors apoptosis, as well as (b) more highly topical areas of apoptosis, telomeres, DNA damage and repair, cell adhesion, angiogenesis, immunity, epigenetics, and the proteasome. * Clinical oncology: In-depth coverage of important concepts such as screening, risk of cancer and prevention, diagnoses, managing cancer patients from start to palliative care and end-of-life pathways. * Chapters highlighting the direct links between cancer research and clinical applications. * New coverage on how cancer drugs are actually used in specific cancer patients, and how therapies are developed and tested. * Systems Biology and cutting edge research areas covered such as RNA interference (RNAi). * Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review. * Quotations have been used in each chapter to introduce basic concepts in an entertaining way. * Supported by a dedicated website at www.blackwellpublishing.com/pelengaris We should list the great reviews we got for first edition which are on the back of the 2nd edition: "A capturing, comprehensive, clearly written and absolutely accurate introduction into cancer biology...This book deserves great praise for the readable presentation of this complex field...the true synthesis of bench and bedside approaches is marvelously achieved." Christian Schmidt, Molecular Cell "Chapters address the issues of cancer diagnosis, treatment, and patient care and set the book apart from general molecular biology references...This book is applicable to both graduate and undergraduate students, and in the context of a research laboratory, this book would be an excellent resource as a reference guide for scientists at all levels." V.Emuss, Institute of Cancer Research, London. Also, from the first edition: "Pelengaris, Khan, and the contributing authors are to be applauded. The Molecular Biology of Cancer is a comprehensive and readable presentation of the many faces of cancer from molecular mechanisms to clinical therapies and diagnostics. This book will be welcomed by neophyte students, established scientists in other fields, and curious physicians." -Dean Felsher, Stanford University  

This book presents a clear and precise discussion of the biochemistry of eukaryotic cells, particularly those of mammalian tissues, relates biochemical events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of abnormal biochemical processes in human disease. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to human diseases.

This book provides biomedical engineers with the premiere reference on medical instrumentation as well as a comprehensive overview of the basic concepts. The revised edition features new material on infant apnea monitors, impedance pneumography, the design of cardiac pacemakers, and disposable defibrillator electrodes and their standards. Each chapter includes new problems and updated reference material that cover the latest medical technologies. The chapters have also been revised with new material in medical imaging, providing biomedical engineers with the most current techniques in the field.

This is an "Introduction to Human Molecular Genetics Second Edition" by Jack J. Pasternak. The Second Edition of this internationally acclaimed text expands its coverage of the molecular genetics of inherited human diseases with the latest research findings and discoveries. Using a unique, systems-based approach, the text offers readers a thorough explanation of the gene discovery process and how defective genes are linked to inherited disease states in major organ and tissue systems. All the latest developments in functional genomics, proteomics, and microarray technology have been thoroughly incorporated into the text. The first part of the text introduces readers to the fundamentals of cytogenetics and Mendelian genetics. Next, techniques and strategies for gene manipulation, mapping, and isolation are examined. Readers will particularly appreciate the text's exceptionally thorough and clear explanation of genetic mapping. The final part features unique coverage of the molecular genetics of distinct biological systems, covering muscle, neurological, eye, cancer, and mitochondrial disorders. Throughout the text, helpful figures and diagrams illustrate and clarify complex material. Readers familiar with the first edition will recognize the text's same lucid and engaging style, and will find a wealth of new and expanded material that brings them fully up to date with a current understanding of the field, including: New chapters on complex genetic disorders, genomic imprinting, and human population genetics. It includes an expanded and fully revised section on clinical genetics, covering diagnostic testing, molecular screening, and various treatments. This text is targeted at upper-level undergraduate students, graduate students, and medical students. It is also an excellent reference for researchers and physicians who need a clinically relevant reference for the molecular genetics of inherited human diseases.

Through analyses of the complex underlying issues, this interdisciplinary volume frames the agenda for dealing with genetic variation and incorporating pharmacogenomics into health care. The three sections of this book, Research Issues, Clinical Issues, and Social Perspectives address key elements integral to a comprehensive discussion of this emerging field. This groundbreaking text...* Examines new research strategies, methodologies, and ethical and social considerations of pharmacogenomics* Addresses practical considerations of anticipated changes in education, training, oversight, guidelines and protocols, and continuing education requirements* Provides analyses of the potential enormous impact of pharmacogenomics, such as in the standard of care and treatment, including perspectives from the fields of anthropology, law, ethics, and economics