Oxford University Press

Provides an international reference on clinical cancer medicine. It combines the experience of the world's leading cancer experts, particularly from leading European centres of excellence, with an approach that emphasizes the importance of the best clinical evidence: the guidelines to management are based on the sum of all the available evidence. For rare tumours, where clinical experience is the main guide to treatment, the editors have ensured that options and alternatives are discussed. There are major sections on all cancer sites, and in each section investigation, epidemiology, pathology, causes and treatment are covered in a consistent manner to aid reference. Quality-of-life and psychosocial issues, palliation, and communication are included.

In recent years the practice of psychiatry has changed fundamentally. Mentally ill people have been moved out of the large institutions, with their clear structures and hierarchies, and into the community. This shift has required the development of new service structures, new facilities, new attitudes and new professional relationships. This book provides the first authoritative, international review of community psychiatry, taking into consideration theoretical as well as clinical issues. The key aim of the book is to review the status of community psychiatry throughout the developed world, presenting a comprehensive and critical exposition of the achievements, limitations and dilemmas in the theoretical base and the practical implementation of a community-based strategy. The book covers the available evidence base, gaps in that evidence base and describes, where possible, best practice for treatment and care. Current areas of theoretical and professional conflict are also covered. There are two main sections of the book; the first describes psychiatry for the community, in which the population needs for psychiatric care are considered. The second major section examines psychiatry in the community, describing how the service systems are designed to meet these needs. The final section of the book examines ethical issues and dilemmas. With 46 chapters from the leading international experts in the field, this book will be essential reading for all those working with the mentally ill in the 21st century.

Most neurological lesions in cancer patients are progressive, have a profound influence on the quality of life and can be fatal. Management of the situation requires rapid identification of the nature and location of the problem as the treatment outcome depends as much on the speed of diagnosis as on the subsequent therapy. While modern neuroimages provides invaluable clues to the diagnosis, they need to be interpreted in the light of clinical data. The clinical examination remains the cornerstone of the differential diagnosis of neurological lesions affecting the cancer patient. Neurological disorders are a consequence not only of primary tumours of the central and peripheral nervous system but also of systemic malignancy. One in five patients with disseminated malignancy develop neurological complications other than neurogenic pain. The majority of neurological problems are a direct consequence of metastatic disease or the result of metabolic disorders. However, some disorders are due to anti-neoplastic treatments or the administration of drugs. The incidence of CNS infections and vascular lesions is also increased in malignant disease, and a small proportion of neurological disorders are paraneoplastic, resulting from a remote effect of cancer on the nervous system. This book, written by a neurologist and an oncologist, aims to help the clinician to identify and locate the underlying neurological lesion in a cancer patient, and to make a quick therapeutic decision. Diagnostic and therapeutic algorithms are included with an emphasis on the more common and potentially treatable conditions. It should be read by neuro-oncologists, medical oncologists, radiation therapists, neurosurgeons and all those involved in the management of cancer patients.

An understanding of the quantum mechanical nature of magnetism has led to the development of new magnetic materials which are used as permanent magnets, sensors, and information storage. Behind these practical applications lie a range of fundamental ideas, including symmetry breaking, order parameters, excitations, frustration, and reduced dimensionality. This superb new textbook presents a logical account of these ideas, staring from basic concepts in electromagnetsim and quantum mechanics. It outlines the origin of magnetic moments in atoms and how these moments can be affected by their local environment inside a crystal. The different types of interactions which can be present between magnetic moments are described. The final chapters of the book are devoted to the magnetic properties of metals, and to the complex behaviour which can occur when competing magnetic interactions are present and/or the system has a reduced dimensionality. Throughout the text, the theorectical principles are applied to real systems. There is substantial discussion of experimental techniques and current reserach topics. The book is copiously illustrated and contains detailed appendices which cover the fundamental principles.

For this fourth edition of Professor Curran's colour atlas of histopathology, the text has been completely revised and there have been additional immunohistological images added to the 804 colour illustrations. The general arrangement of the contents has been retained, with a chapter on each of the main systems or organs of the body. There is an introductory chapter of a general nature which demonstrates the more important reactions of the tissues in disease and at the same time teaches the student the basic language of histopathology, thereby enabling him or her to read and assess the significance of changes in the tissue as revealed by microscopy. Most of the conditions are common or fairly common diseases, but occasional rare lesions are included. The book is primarily an atlas, the primary purpose of which is to convey information in visual form. It is meant to complement existing textbooks. A new comprehensive index has been prepared for this edition. This book is intended for primarily intended for undergraduate medical students but as with its predecessors, likely to prove useful to postgraduate students in training in pathology or other clinical disciplines.

Molecular medicine is well developed in the West. However, due to a lack of exposure to the discipline, its impact on diseases in the tropics is not very widely appreciated. This book intends to fil this gap, particularly for graduate and postgraduate medical students. It summarizes the state of the state of the art of the major killers in the tropics.

Formerly the titled Textbook of Dental Pharmacology and Thearapeutics, a new team of authors has extensively revised this successful text, incorporating the many advances in this field over the last few years. In 27 chapters, this book comprehensively covers both the basic and applied pharmacology required in modern dental courses, emphasising those topics which are particularly relevant to dental practice. With new key fact boxes, clinical cases and further reading, this new edition will be easier and more fun to use for the dental student.

The first edition of the "Oxford Textbook of Clinical Nephrology" established itself as a clinical reference text for practising nephrologists worldwide. The second edition comes five years later, during which time there have been significant advances in the understanding of the pathogenesis of renal disease and advances in therapy. The text argues that placing existing treatment on a firm scientific basis or stopping ineffective or dangerous treatment is as important as introducing proven new therapies, and all the contributors have taken this fully into account.

Since its publication in 1987, Methods for the economic evaluation of health care programmes has become the standard textbook in this field world-wide Over the past ten years, the field of economic evaluation in health care has expanded considerably, with a rapid rise in the number of published studies, and wider recognition of their use in health care decision-making. Developments in economic evaluation have also led to the publication of several guidelines for study methodology, most recently those proposed by the United States Public Health Services Panel. The new edition of Methods for the economic evaluation of health care programmes follows the same basic structure as the first edition. The key methodological principles are outlined using a critical appraisal checklist that can be applied to any published study. The methodological features of the basic forms of analysis (cost analysis, cost-effectiveness analysis, cost-utility analysis, and cost-benefit analysis) are then explained in more detail. The book has been greatly revised and enlarged, especially with respect to cost-utility and cost- benefit analysis, where major methodological developments have taken place. New to this edition are chapters on collecting and analysing data, and presenting and using economic evaluation results. The new edition will be required reading for anyone commissioning, undertaking, or using economic evaluations in health care, and will be popular with health service professionals, health economists, and health-care decision makers.

This comprehensive book describes modern electrochemistry, from fundamental principles to the methods that can be used to study electrode and electrochemical processes, and finally, at the wide-ranging applications in sensors, industry, corrosion, and bioelectrochemistry. The breadth of coverage ensures that this volume will be valuable not only to undergraduate and graduate students, but also to research workers.

The four Primary Surgery volumes are manuals written for the non-specialist doctor and medical students. Two other volumes Trauma and Primary Anaesthesia have already been published and a fourth, Primary Mother Care is in preparation. The manuals describe what a doctor can do if s/he cannot refer a patient, both in emergency and for 'cold surgery'. Surgery has become fragmented into many specialties, and these manuals select methods of which the generalist can make good use. Although common problems such as Caesarean section, the resection of dead gut, and the release of pus from infected bones are highlighted, it is recognized that rare problems are fairly common, and thus the manuals aim to be comprehensive. The organization and equipment found within an operating theatre is described, and an extensive equipment list is provided. The previous volumes have been well-received, as a reader from Africa testifies: "With the volume on Trauma (which never leaves the theatre) open, my colleagues and I have done several operations successfully, which we previously knew nothing about. I was especially impressed with the descriptions of how to make burr holes for intracranial bleeding. Following the instructions, a patient who had been unconscious for 10 days woke up after the evacuation of bilateral subdural haematosas."

The result of ten years' detailed research, this is a complete and detailed system of trauma methods which the non-specialist general duty doctor can use to treat all human injuries that might benefit from his care. It is designed mainly for medical schools and hospitals in the developing world, but any doctor who is not a trauma specialist will find it useful. A valuable feature is a system of closed methods for all fractures which can be treated this way, and there is an extensive chapter on the treatment of burns. The book is published in collaboration with the Deutsche Gestellschaft fur Technische Zusammenarbeit and the Kenyan Ministry of Health, and is part of a complete series on surgery, anaesthesia and obstetrics for hospitals in the developing world.

The application of radiation to medical problems plays an ever-increasing role in diagnosis and treatment of disease. It is essential that medical physicists have the knowledge, understanding and practical skills to implement radiation protection as new techniques are developed. Practical Radiation Protection in Healthcare provides a practical guide for medical physicists and others involved with radiation protection in the healthcare environment. The guidance is based on principles set out in current recommendations of the International Commission for Radiological Protection and methods developed by a variety of professional bodies. Written by practitioners experienced in the field this practical reference manual covers both established techniques and new areas of application. This new edition has be fully revised and updated to cover new requirements linked to the increased knowledge of radiation effects, and the development of new technology. Each specialist area is covered in a separate chapter to allow easy reference with individual chapters being assigned to different types of non-ionising radiations. Tabulated data is included to allow the reader to carry out calculations for situations encountered frequently without reference to further texts.

This book represents the final work of the late Professor C. David Marsden, who was the most influential figure in the field of movement disorders, in terms of his contributions to both research and clinical practice, in the modern era. It was conceived and written by David Marsden and his colleague at the Institute of Neurology, Prof. Ivan Donaldson. It was their intention that this would be the most comprehensive book on movement disorders and also that it would serve as the 'clinical Bible' for the management of these conditions. It provides a masterly survey of the entire topic, which has been made possible only by vast laboratory and bedside experience. Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to rare, and very rare conditions such as Niemann-Pick disease. Chapters follow a structured format with historical overviews, definitions, clinical features, differential diagnosis, investigations and treatment covered in a structured way. It is extensively illustrated with many original photographs and diagrams of historical significance. Among these illustrations are still images of some original film clips of some of Dr. Marsden's patients published here for the first time. Comprehensively referenced and updated by experts from the Institute of Neurology at Queen Square, this book is a valuable reference for, not just movement disorder specialists and researchers, but also for clinicians who care for patients with movement disorders.