Springer London Ltd

Vascular care has evolved from conservative therapy and open surgical therapy to a minimally invasive approach using endovascular techniques, laparoscopic or thoracoscopic techniques as well as hybrids of open and endovascular techniques. This volume provides up-to-the-minute information and details new developments and procedures.

Atherosclerosis: Clinical Perspectives Through Imaging is aimed at practicing clinicians and relies on didactic tabular and bullet points and a host of fine imagery describing the common features of the imaging of atherosclerosis, enabling the reader to understand more about the advantages and limitations of each modality in investigating athersclosis. Edited by and contributed to by a host of international experts in cardiac imaging, this book is a must read by all who image the heart.

Peripheral Nerve Injuries: A Clinical Guide is a fully illustrated and informative reference on injuries within the peripheral nervous system. It incorporates new knowledge in molecular and cellular events which underlie the response of nerves to injury, regeneration and neuropathic pain. Written by a leading expert in the field, Peripheral Nerve Injuries: A Clinical Guide, is a valuable resource for surgeons in residence and training.

"Dynamic Structure of NREM Sleep" is a concise guide to Cyclic Alternating Pattern (CAP) phenomenology and slow wave homeostasis. It presents an original approach to a specialized aspect of sleep neuroscience in a concise and easy-to-read format. The authors are specialists in the field of sleep neuroscience and lend a new perspective to the benefits of slow wave activity during sleep. The main feature of this discussion is that slow wave activity increases as a function of previous wakefulness and it gradually decreases in the course of sleep. Alongside developing this idea, this book covers the entire range of sleep issues from basic structure to function in comprehensive detail. "Dynamic Structure of NREM Sleep" is valuable reading for neurologists, sleep neuroscientists and those with an interest in the field.

Progressive multiple sclerosis places huge burdens on individuals, carers and society and treatment options are currently limited. However, there have been significant recent advances in understanding progressive disease and this book draws together the field into a single accessible, clinically focused text. Progressive Multiple Sclerosis sets out the basic science, pathology, epidemiology and treatment possibilities in progressive multiple sclerosis. The biological processes underlying disease progression are elucidated and specific pathophysiological mechanisms. The basic science of axonal degeneration and clinical understanding of progressive multiple sclerosis is discussed in the context of emerging and future therapies for disease progression as well as discussion of how trials might be conducted for progressive multiple sclerosis and an overview of biomarkers for the disease. Existing symptomatic therapies for progressive multiple sclerosis are discussed in detail.

This handbook is a guide to best practice in interventions commonly encountered in the ICU. It is clinically orientated providing :step-by-step explanations and illustrations of most invasive procedures, check lists to make sure the indication is right, check lists to ensure appropriate assessment once the procedure has been carried out. The information is easily accessible providing practical advice and essential background for every member of the multi-disciplinary team caring for critically ill patients. It will serve the senior consultant who has not performed a procedure for some time as well as the junior doctor in need of an aide memoire.

Laser technology is constantly evolving and progressing. The use of laser therapy is vastly expanding and for this reason a medical book of this magnitude is necessary. Lasers and Light Therapy includes an up-to-date comprehensive look at lasers and light therapy not only in the field of Cutaneous Laser Surgery, but in other medical specialties as well.

Perioperative Medicine uses a concise, highly practical, bulleted format designed to ensure rapid comprehension of key concepts and reinforce the reader's understanding of complex topics in perioperative medicine. It contains authoritative, up-to-date coverage of the most essential concepts in perioperative care from preoperative risk assessment to postoperative follow-up. The Editor and his contributors use their expert insight and experience to provide an in-depth review of comorbid conditions, patient and surgery-specific risk assessment, and common postoperative complications. This new book reviews recent developments in the field, including published guidelines, and emphasizes an evidence-based, cost-effective approach designed to ensure quality, patient safety, and optimal outcomes. It is intended for use by hospitalists, general internists and subspecialists as well as anesthesiologists, surgeons, and residents in training who are caring for patients before and after surgery.

Neurodegenerative Disorders provides an accessible guide to the commonest neurodegenerative diseases, outlining the main clinical features, treatment options and outcomes of the conditions most frequently encountered in clinical practice. Beginning with an overview of the general principles that underlie degeneration, and the contribution of established and new diagnostics techniques, the book goes on to describe the most common neurodegenerative conditions including Alzheimer Disease; Dementia and Cerebrovascular Disease; Parkinson's Disease; Fronto-Temporal Dementia; Amyotrophic Lateral Sclerosis; Huntington's Disease; Parkinsonism Plus syndromes and Prion Diseases. Final chapters cover important management issues including the use of palliative care strategies, advance directives and competence. Written by experts in the field internationally Neurodegenerative Disorders is a practical guide for clinicians that will be indispensable for the management of these conditions.

In this book, we discuss how children grow, how to measure this and how to decide whether development falls within normal parameters. It is important not to over-investigate, but, if necessary, which tests and imaging should we choose? We consider how best to look after our patients in hospital, out-patients departments and at home. This leads us to consider problems with the norm, including the more generalised bone and cartilage disorders, most now genetically determined. The section concludes with chapters on infection, arthritis and that most emotive of topics, the tumours of childhood.

Case Studies in Abdominal and Pelvic Imaging presents 100 case studies, covering both common every-day conditions of the abdomen and pelvis, as well as less common cases that junior doctors and radiologists in training should be aware of. Compiled by experts in the field, Case Studies in Abdominal and Pelvic Imaging uses the most up-to-date and high quality images, including plain films, CT scans, MRI scans and the occasional nuclear medicine image where relevant. Each case is presented in a pedagogical style, with 1-4 images and accompanying questions, followed by answers and further relevant images. This is then augmented by an explanation of the imaging and key teaching points with references for further reading, making this book a valuable learning guide in an accessible form.

The Second Edition of A-Z of Neurological Practice builds on the previous edition with revised and updated information in a high density but easily accessible format to provide a quick and ready reference for busy clinicians of all degrees of experience. Entries for specific neurological conditions are uniformly structured indicating: Pathophysiology; Clinical Features; Investigations and Diagnosis; Differential Diagnosis; Treatment and Prognosis. Key references are cited throughout and all entries are cross referenced. A-Z of Neurological Practice, Second Edition is a practical, authoritative guide that will become an invaluable resource for neurologists in clinical practice, neurology trainees and all those involved with the treatment of neurological disorders.

Clinical management and signs are the focus of this practical cardiogenetic reference for those who are involved in the care for cardiac patients with a genetic disease. With detailed discussion of the basic science of cardiogenetics in order to assist in the clinical understanding of the topic. The genetic causes of various cardiovascular diseases are explained in a concise clinical way that reinforces the current management doctrine in a practical manner. The authors will cover the principles of molecular genetics in general but also specific to cardiac diseases. They will discuss the etiology, pathogenesis, pathophysiology, clinical presentation, clinical diagnosis, molecular diagnosis and treatment of each cardiogenetic disease separately. Therapy advice, ICD indications, indications for and manner of further family investigation will all be covered, while each chapter will also contain take-home messages to reinforce the key points. The chapters reviewing the different diseases will each contain a table describing the genes involved in each. Each chapter will also contain specific illustrations, cumulatively giving a complete, practical review of each cardiogenetic disease separately. Special emphasis will be given to advice on how to diagnose and manage cardiogenetic diseases in clinical practice, which genes should be investigated and why, and the pros and cons of genetic testing. Guidelines for investigation in families with sudden cardiac death at young age will also be included. This book will be written for the general cardiologist and the clinical geneticist who is involved in cardiac patients and will provide answers to question such as: Which genes are involved and which mutations? What is the effect of the mutation at cellular level? Which genes should be tested and why? What is the value of a molecular diagnosis? Does it influence therapy? And when should the first degree relatives be tested and in which way?

This Textbook will give the reader a detailed understanding of the use of 3D echo covering a wide range of topics; from the evolution of RT3D echo to the role of RT3D echo in drug trials, including chapters on the Principles of Transthoracic and Transesophageal Real-time 3D echocardiography. Other books in this area are more varied, less specific.

This book will provide both an evidence base and practical recommendations for the treatment of patients with congenital heart disease. It will be a resource to all health care providers, including pediatric cardiologists, pediatric intensivists, pediatric heart surgeons, fetal specialists, maternal fetal medicine specialists, neonatologists, nurses, advanced practice nurses, in addition to trainees in the field. It will summarize world knowledge on the topic of heart failure in patients with congenital heart disease. It will provide an in depth analysis of the current methods of diagnosis and treatment of heart failure. Now that surgical results are at record success rates, more patients with congenital heart disease are surviving, and thus at risk for sequelae from their disease, including heart failure. It will provide evidence based and practical recommendations to the practitioner for the management of heart failure signs and symptoms.

The aim of this book is to provide a systematic approach to echocardiographic diagnosis based upon a comprehensive understanding of cardiac anatomy. We shall provide abundant anatomic correlates of echocardiographic findings throughout the book.The book will be divided into three sections. Each chapter will cover both normal and pathological findings on echocardiography with anatomic correlation. The first section will address the normal findings which can be appreciated by current day echocardiography. The impact of aging on cardiac structure and function will also be covered in this section. In the second section, specific cardiac diseases will be discussed. The differentiating features between normal and pathologic conditions will be discussed. The last section will address specific clinical settings where echocardiography is pivotal for diagnosis and patient management.

This book is structured into eight chapters: 1 Skin anatomy. This chapter is intended to describe the pertinent anatomy related to IPL applications. In addition to the described main structural elements of the skin, the chapter has important points about skin aging and histological aspects which gives the reader a better understanding of the etiology of skin lesions and the need for Intense Pulsed Light (IPL) treatment; and, 2 Light-tissue interaction. This chapter describes the interaction between IPL and different skin structures. Target skin structures (chromophores) are described in detail. The results of this interaction are detailed as being important to understanding the goals and principles of IPL treatment. It also includes: 3 IPL safety and legal issues. This chapter describes the needs of the environment for a safe treatment. The necessary equipment and things to avoid pitfalls which may lead to lawsuits are detailed. Several aspects of IPL legal issues are also described: how to avoid medical liabilities and how to manage them are also included in this chapter; and, 4 Patient selection. This chapter describes the pearls and pitfalls in selecting patients for IPL treatment. This is not an easy task and proper patient selection is extremely important to have satisfied patients. Problematic patient types are also described here. It also includes: 5 Skin rejuvenation. This chapter starts with a description of skin aging. Intrinsic and extrinsic mechanisms are detailed. The most common skin lesions related to aging that can benefit from IPL treatment for rejuvenation are detailed. The chapter continues with treatment protocols which describe strategies for achieving optimal results. A review of the literature is included, presenting the treatment parameters of different studies and their results; and, 6 Hair removal. This chapter starts with a description of the hair follicle cycle, hair types and important structures for treatment. Treatment strategies are emphasized and detailed, starting from choosing the right parameters to post-treatment recommendations. A literature review is presented regarding treatment parameters and results according to different authors. It also includes: 7 Vascular lesions treatment. This chapter describes the types of vascular lesions that can benefit from IPL treatment. The treatment protocol is emphasized and all the steps for performing this application are described in detail. A literature review is presented and different results are compared regarding treatment parameters; and, 8 Complications. It is inevitable that any medical treatment can end with complications. The possible complications of the most common IPL applications (skin rejuvenation, hair removal, pigmented and vascular lesion treatment) are detailed. The way to avoid them and how to handle them is also described. At the end of each chapter, there is a section on the practical points highlighting the most important points of the chapter. An extensive literature review of this technology is presented alongside numerous illustrations, tables and color pictures. This book will benefit any doctor or healthcare professional who uses IPL for cosmetic purposes, such as plastic surgeons, dermatologists, ophthalmologists, maxillofacial surgeons and otolaryngologists dealing with aesthetics of the face, as well as residents interested in learning the subject.

Over the past ?fty years, advanced techniques and strategies have arisen in the ?eld of myocardial protection. Meticulous trials, focusing on pulmonary protection during heart surgery requiring cardiopulmonary bypass (CPB), have been missing. This te- book is intended to serve as a useful tool to spread information on strategies for lung protection during heart surgery with CPB. Emphasis on pulmonary protection will be turned to lung perfusion as an adjunct for minimizing the deleterious effects of pulmonary ischemia-reperfusion injury in heart surgery. Many renowned authors have contributed by presenting their expe- ence on lung perfusion in basic research and clinical trials. Furthermore, they have enlightened the quality of this textbook with new ideas, concepts, and future perspectives. The scope of this textbook is of interest to different professionals, such as card- vascular surgeons, pulmonary surgeons, transplantation physicians, cardiothoracic anesthesiologists, intensive care physicians, cardiothoracic fellows, radiologists, basic sciences physicians, cardiologists, pulmonary medicine physicians, perfusi- ists, nurses, students, and researchers. This textbook has 7 sections, aimed at addressing general and speci?c aspects of pulmonary protection during heart surgery with CPB. The ?rst section on general concepts provides information about anatomic, physiologic, histologic, molecular, and radiologic considerations regarding the lungs. The second section focuses on ischemia-reperfusion injury and is composed of several interesting chapters, addressing the basic science aspects of pulmonary p- tection, as well as experimental and clinical experiences from different heart surgery centers worldwide.