Springer Verlag Japan

This book is a knowledge-based text that covers the anatomy, neurophysiology, and neuropharmacology needed to carry out the necessary management and cerebrospinal protection during neuroanesthesia. Especially to make the subject of neuroanesthesia more approachable, we introduce surgical measures utilized in neurosurgery, cardiovascular surgery, neuromodulation, and related procedures. The main purpose of neuroanesthesia/neurocritical care is to deliver cerebrospinal protection in neurosurgical and cardiovascular surgeries. How should we select the best anesthetic management to prevent neurological complications for patients who, for instance, undergo different types of surgery for subarachnoid hemorrhage, stroke, head trauma, carotid endarterectomy, or cardiovascular surgery under cardiopulmonary bypass? These pathological conditions include the risk of transient cerebrospinal ischemia, and if our management is not precise, it may induce serious neurological sequelae. Although there is an urgent need to establish the treatment and elucidate the molecular mechanisms of cerebrospinal injury, many components are intertwined, making this a challenge we have not completely solved yet. This volume makes the management of neuroanesthesia more accessible not only for primary residents but also for specialists, providing a valuable resource on the current perspectives of neuroanesthesia.

This book focuses on a novel series of minimally invasive surgeries performed without gas insufflation and through a single port using the RoboSurgeon system. The concept of RoboSurgeon surgery involves a degree of "robotization" of the operator and participants. The operator, wearing a head-mounted display, uses robot-like handheld instruments. The endoscope is controlled by the movement of the operator's head using a gyro-sensor system. All participants wearing head-mounted displays can see the same images as the operator does. Although this surgery is mainly intended for urological cancers, it may also be applicable for various operations concerning other urological diseases, as well as for the treatment of diseases in different medical fields. The system has the potential to become the new standard in robotic surgery. This solution may be a boon to many patients around the world, especially in the aging societies many countries are now facing.

Reduced port laparoscopic surgery is a fast-developing topic for the laparoscopic surgeon, with the emergence of a number of new techniques as well as new instruments. Edited by surgeons who have pioneered the single-incision approach, this volume provides extensive information for the beginning surgeon, examining different operation techniques and covering the advantages and pitfalls of reduced port laparoscopic surgery. In addition, the text provides the foundation for new ideas to further develop skills for the advanced laparoscopic surgeon.

All of us in biomedicine understand the urgency of getting experimental results into print as quickly as possible. Yet this critical step in the cascade from research conception to publication receives almost no attention in our formal training. It is as if we have been put to sea without a compass. Our collective failure to achieve widespread literacy in our own language - Biomedical Language - seriously impedes the important process of d- seminating new biomedical knowledge and thereby improving the human condition. It is also a significant personal concern for researchers and clinicians in the highly competitive, publish-or-perish environment of c- temporary academia. Of course, if we are clever or lucky enough to come up with that Nobel Prize-winning discovery, great science will carry the day and we are likely to get published even if our writing is fairly horrid. But most of us who publish are "bread-and-butter" scientists. We compete for space in journals which may only accept 10% or 20% of the submissions that they receive each year. For us, convincing, engaging writing will make the difference between being published or rejected, or at least it will make the difference between being published on ? rst submission or having to go through a number of revisions (or journals). None of this is to propose that good writing can make a silk purse out of a sow's ear. Scienti? c content is the sine qua non of biomedical writing.

The initial distribution volume of glucose (IDVG) is believed to be clinically relevant as a marker of cardiovascular and fluid management in critically ill patients without a significant modification of glucose metabolism. This book covers all aspects of IDVG measurement, including the basic concept, its relationship with other fluid volumes, and the clinical application of this technique in the intensive care unit.

Combining harmonic technology and an ultrasound contrast agent, harmonic imaging now plays a vital role in the diagnosis and treatment of hepatic tumors. Contrast harmonic imaging is especially valuable in cases of hepatocellular carcinoma (HCC), the incidence of which has risen dramatically in Europe, North America, and Asia in recent years. Harmonic imaging is bringing about revolutionary changes in the diagnosis and treatment of HCC, and this book provides the most up-to-date information and guidelines for effective use of this superior technique. Generously illustrated with photographs and diagrams, with accompanying text by a leading expert in the field, this acclaimed book is a valuable state-of-the-art resource for clinicians and researchers in radiology and internal medicine, including hepatology and gastroenterology.

Since the first successful digit replantation in Japan in 1965, the field of microvascular surgery has rapidly progressed throughout Japan and the world. Experimental and Clinical Reconstructive Microsurgery draws on the experience of a large number of experts in the areas of experimental microsurgery, limb and digit replantation, and composite tissue transplantation. The result is an extensive monograph covering the history and future prospects of microsurgery, essential microsurgical techniques for laboratory research, and the fundamental methods of harvesting tissues and their grafting techniques. Because the field of microsurgery includes a broad range of clinical disciplines, this book is a valuable resource to all orthopedic, traumatic, and plastic surgeons with an interest in microsurgery.

Since the discovery of superoxide dismutase more than three decades ago, there has been rapid growth in the knowledge of oxidative stress and disease. This volume containing the proceedings of the 13th Yamaguchi Symposium on Liver Disease includes discussion of the direct cellular effects of hepatitis C virus (HCV) proteins on hepatocytes and reviews evidence that oxidative stress caused primarily by the HCV core protein plays a key role in disease pathogenesis. Also included are chapters on new aspects of oxidative stress and liver disease such as carbon monoxide as a regulator of liver microcirculation, hepatic iron accumulation and the incidence of hepatocellular carcinoma, and oxidative stress in the absence of inflammation in hepatocarcinogenesis. This collection of papers from the Yamaguchi Symposium creates a valuable reference resource for physicians and hepatologists.

Peripheral nerve injury and entrapment neuropathy often are complicated by injury to adjacent tissue such as bone, joints, blood vessels, and tendons. Clinicians who provide primary care in these areas require extensive knowledge of methods for treating wounds and nerve injuries. The most important element in the treatment of peripheral nerve injury is appropriate surgical repair or functional reconstruction; postoperative physical and occupational therapy are also necessary. This book summarizes current topics in Japan and other countries in the field of surgical nerve repair, including selection of treatment methods for peripheral nerve paralysis, practical issues in surgery, and aspects of postoperative care. The importance of evidence-based medicine is emphasized, with appropriate therapy decided on the basis of objective data. The book has a broad appeal to include general clinicians, clinical trainees, and allied health-care professionals.