Ostetricia

Challenging Concepts in Obstetrics and Gynaecology is a case-based guide to difficult scenarios faced in both fields, covering many of the major sub-speciality areas of each. The 24 cases have been selected to cover a spectrum of challenges in obstetrics and gynaecology. Recognising that any attempt to cover the whole curriculum is impossible, the authors have instead chosen specific, challenging scenarios that are commonly encountered in clinical practice, but by no means have simple answers or outcomes. Complex cases are examined from a multidisciplinary approach with consideration of diagnostic procedures, practical skills, evidence base, and the application of national and international guidelines. There is also a summary of evidence from the medical literature in various subspecialty areas of obstetrics and gynaecology, alongside current controversies in management. Cases are punctuated by easy-to-read "Learning Points", "Clinical Tips", and "Evidence Base" boxes, speeding the learning process as well as providing a handy dip-into guide for those just refreshing their memory. Each case is set off by an 'Expert Commentary' written by an internationally-renowned expert in each field, leaving the reader with both a solid base of knowledge and a nuanced view of current challenges in obstetrics and gynaecology. This collaboration between trainees and experts provides a unique insight into the management of complex and often rare but important obstetrics and gynaecology cases, within a highly user-friendly format and a ready-made means of self-learning and self-testing. Challenging Concepts in Obstetrics and Gynaecologymakes a useful, relevant and interesting read, enabling the reader to readily transfer the knowledge gained to everyday clinical practice.

Texts on inborn errors of metabolism (IEMs) have traditionally focused on classical biochemistry, clinical presentation, and standard treatment approaches. Inborn Errors of Metabolism is an expansion on this model, one that establishes an innovative pathway approach and provides a new authority on this family of disease. Alongside the standard cadre of molecular and clinical underpinnings, this volume includes coverage of newborn screenings and an overarching treatment of IEMs as complex diseases - how basic alterations can lead to complex secondary and tertiary effects in metabolism that contribute to increasingly recognized natural histories of disease.

This book examines the role of psychopharmacological treatment in a range of disorders that may be encountered during pregnancy, including major depressive disorders, anxiety disorders, bipolar affective disorder, schizophrenia, eating disorders and substance abuse. The natural history of each condition pre and post-partum is analyzed and the evidence for the efficacy of drug treatments, evaluated. Special attention is paid to the potential dangers of different treatment options for both mother and fetus, covering risks of malformation, pregnancy and obstetric risks, neonatal risks and possible long-term consequences. The risks of not treating a particular condition are also analyzed. On the basis of the available evidence, management guidelines are provided that additionally take into account non-pharmacological options. Closing chapters consider the value of complementary and alternative medicine and ECT and explore future research directions.