Neurologia

This volume in the "Handbook of Clinical Neurology" (Series Editors: Michael J. Aminoff, Department of Neurology, University of California, San Francisco, USA; Francois Boller, Bethesda, USA; Dick F. Swaab, Netherlands Institute for Neuroscience, Amsterdam, the Netherlands) deals with neuropathology, physiopathology, biology, clinics, and imaging of all or most dementing disorders that are presently known. It also includes chapters on the legal and ethical issues to give the health care worker a general view on diseases that are not only scientific riddles, but also the cause of affliction of many patients and of their families. Recently several major new advances in understanding have been made and are covereed in this volume (for example the progranulin mutation and the role of TDP-43). All those dealing with dementia, at whatever level of expertise, may find this volume of value.

Neurologic Complications of Cancer reviews the impact of cancer on the nervous system. It examines the diagnosis and management of neurological complications of specific types of cancer, as well as the side effects of oncological treatments. Updated with approximately 30% new material it includes new diagnostic techniques and treatments.

Everything you need to know about neuromuscular disease--in one concise, full-color volume "...this book will become an indispensable resource for clinicians involved in the diagnosis and management of patients with neuromuscular diseases, as well as for scientists working on the nature and pathogenesis of these disorders. It is a much-needed and welcome addition to the neurological literature and will rapidly gain acceptance as a standard work of reference."--Michael J. Aminoff, MD, DSc, FRCP, (from the foreword) Neuromuscular Disorders is comprehensive in scope, yet concise enough to serve as a valuable point-of-care guide for your day-to-day clinical practice. Grounded by numerous reference sources and enhanced by the experience of two seasoned clinicians, this text provides a pragmatic approach to the evaluation and management of neuromuscular disease. Here, in a single source, you'll get an insightful look at both nerve and muscle conditions, ranging from motor neuron diseases to neuropathies, neuromuscular junction disorders, and myopathies. The book opens with the clinical and laboratory approach to patients with neuromuscular disease, covering electrodiagnostic testing, nerve conduction studies, and muscle and nerve histopathology. With an emphasis on effective diagnosis and treatment, the substance of the text examines the full spectrum of specific neuromuscular diseases, giving you the "big picture" of the discipline in a way that no other text can match. FEATURES: Convenient coverage of both nerve, muscle and neuromuscular transmission disorders--both primary and secondary neuromuscular diseases Specific disease sections encompass the range of conditions likely to be encountered in clinical practice, including amyotrophic lateral sclerosis, myasthenia gravis, radiculopathies and plexopathies, mononeuropathies, various polyneuropathies, toxic myopathies, and dozens more The very latest diagnosis and treatment recommendations and protocols based on the most recent clinical literature and research Well-illustrated with EMGs, histopathology, and clinical photos

Neonatal Cerebral Investigation reviews all aspects of the investigation of the neonatal brain, bringing together diagnostic and prognostic information in a highly illustrated and practical text. An introductory section covers the basic principles of ultrasound, EEG, CFM and MR imaging and spectroscopy. These chapters are followed by a detailed review of normal neonatal imaging appearances and normal EEG, artefactual imaging appearances and imaging of various stages of the immature brain. Subsequent chapters discuss pre-term and term screening and review the imaging appearances in a variety of clinical conditions such as suspected seizure, suspected infection and enlarging head. Highly illustrated with over 400 ultrasound and MRI scans and EEG and CFM traces and providing detailed diagnostic and prognostic information on a wide range of clinical problems, Neonatal Cerebral Investigation provides the reader with a comprehensive overview of all aspects of investigation of the newborn baby with a potential neurological problem.

Come si formano le relazioni umane, quale impatto hanno su di noi e in che modo cambiano l'architettura e il funzionamento del

This concise handbook provides practical, up-to-date clinical guidance on effectively selecting, prescribing and monitoring antiepileptic drugs (AEDs). The book provides comprehensive coverage of current treatment options, and in addition to a formal discussion of the basic pharmacology of each antiepileptic drug, the text also discusses how to choose pharmacotherapies depending upon underlying medical conditions and the type of epilepsy. The advantages and disadvantages of various drug therapies are reviewed and clear guidance is given as to which drugs should be used in various medical conditions.

Since the first edition of this book was published in 1992, the number of pharmacological therapies available for treating neurological disorders has grown exponentially. This new edition brings the book fully up-to-date, and features PET scans to illustrate brain action, and new chapters on practical therapeutics and clinical trials.

The introduction of the endoscope for neurosurgical procedures began with great promise. It was developed to provide a magnified anatomical view of the ventricular system in a minimally invasive manner. The early endoscopes were too primitive for the majority of procedures performed today. The advent of illumination, optical systems, and modern endoscopes allow the neurosurgeon to perform these previously inoperable cases. This book introduces all aspects of the modern endoscope system, physics of optics, and all the techniques of intracranial neuroendoscopy. This is a must-have book for all levels of surgeons, residents, operating room staff, and anyone who wants to learn about endoscopy and its potential applications.

Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure.This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). The book should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering.This book covers a wide range of topics from molecular to seizure predictions and brain implants to control seizures. Contributors to this book are top experts at the forefront of computational epilepsy research. Chapter contents are highly relevant to both basic and clinical epilepsy researchers.

Epilepsy is one of the most common neurological disorders, with a prevalence of 4-10/1000 and an incidence of 50-70/100,000 per year. It is often life-long, can appear at any age and includes a diverse group of neurological disorders, which present considerable challenges in diagnosis and management. Therefore, it is a condition that will frequently be seen by GPs and by a wide range of specialist physicians such as neurologists, psychiatrists, neurosurgeons, paediatricians, geriatricians as well as allied health professionals such as nurses (in particular epilepsy specialist nurses), EEG technicians, neuropsychologists and researchers with an interest in epilepsy. The diversity of epilepsy syndromes makes it difficult to achieve an adequate level of knowledge and expertise in their management. Epilepsy is a comprehensive handbook which guides the reader though all aspects of epilepsy, both practical and academic, covering all aspects of diagnosis and management of the patient with epilepsy in a clear, concise and practical fashion. The book appeals to a wide audience by teaching a simple but highly practical method to approaching the classification and diagnosis of epilepsy, and then provides patient-centred information on pharmacological and non-pharmacological management.

Written by a practicing critical care neurologist, this books includes a historical overview of the concepts of consciousness and unconsciousness, principles of neurologic examination of the comatose patient including instruction of a new coma scale - the 'FOUR Score', interpretation of neuroimaging and its role in daily practice and decision making, management in the emergency room and ICU and long-term supportive care and approach to communication with family members and end-of-life decisions. It also discusses landmark legal cases and ethical problems and a chapter is devoted to the public perception of coma.

This third edition of one of the most popular titles in the at a Glance series contains essential integrated information on anatomy, biochemistry, physiology and pharmacology to provide a review of the structure and function of the nervous system. Neuroscience at a Glance is the perfect introduction and revision aid to this notoriously difficult subject area and features: * New chapters on consciousness, memory, emotion and drug addiction, and imaging the nervous system * Highly visual presentation with full-colour illustrations and the inclusion of high-quality CT and other neurological scans * Self-assessment case studies to make revision more rewarding * A companion website at www.medicalneuroscience.com with self-assessment, case studies, a glossary, further reading and other useful information. Neuroscience at a Glance will appeal to medical students, biomedical science students and junior doctors. In addition, the text is a suitable companion for nurses and other students of allied health.

Thoroughly updated for its Fourth Edition, this best-selling pocket reference is a practical point-of-care guide to the diagnosis and management of epilepsy. In an easy-to-use outline format, the book provides complete, clinically focused information on seizure classification, epilepsies with different ages of onset, situation-related epilepsy, diagnosis and differential diagnosis, and all available drug treatments, including dosages, side effects, and drug interactions. This edition's updated coverage of drug therapy includes current American Academy of Neurology guidelines, new drugs, newly approved indications, new information on pharmacokinetics, and results of six registries of antiepileptic drugs in pregnancy. New information on the genetics and molecular biology of several epilepsy syndromes is also included.

Written by an eminent authority from the American Academy of Neurology's Committee on Ethics, Law, and Humanities, this book is an excellent text for all clinicians interested in ethical decision-making. The book features outstanding presentations on dying and palliative care, physician-assisted suicide and voluntary active euthanasia, medical futility, and the relationship between ethics and the law. New chapters in this edition discuss how clinicians resolve ethical dilemmas in practice and explore ethical issues in neuroscience research. Other highlights include updated material on palliative sedation, advance directives, ICU withdrawal of life-sustaining therapy, gene therapy, the very-low-birth-weight premature infant, the developmentally disabled patient, informed consent, organizational ethics, brain death controversies, and fMRI and PET studies relating to persistent vegetative state.