Neurologia

This exciting and comprehensive volume examines the past decade's clinical and scientific advances in treatment and management strategies for neuromuscular disorders. These developments, affecting current patient evaluation and management, have generated innovative diagnostic methods, new and effective therapies, and new management strategies in the field. This volume explains all the recent breakthroughs and presents them in a clinically relevant way. Chapters written by internationally recognized experts cover all the major neuromuscular diseases. Each chapter has three main sections: scientific background, practical application including diagnosis and treatment, and future directions for basic and clinical research

This reference provides information on the historical, biological, immunobiological, and pathophysiological background of a range of disorders, including multiple sclerosis. Written by a recognized experts, the book also focuses on the use of surrogate disease markers, and the advent of disease-modifying therapies.

Transcranial Magnetic Stimulation (TMS) is a method for stimulating the cerebral cortex through the intact skull by use of a coil delivering a rapidly changing magnetic field. It has applications in neuropsychiatric diagnosis, and in psychiatric therapy, using around one million times less energy than is required for traditional electroconvulsive therapy. Bringing together the basic science, fundamental principles, and essential practicalities of TMS, this book should prove useful to all users whether they are using the technique clinically or in research. The final two sections then bring together current up to date knowledge of applications of the technique. This handbook offers a companion to users of TMS in all departments of neurology, neurophysiology, neuropsychology, and psychiatry.

From pediatric to the elderly, from contractible to refractive, epilepsy is an illness that manifests in many forms and across a range of demographics. In this fascinating volume, the author details more than one hundred instances where health care practitioners faced unusual challenges in treating the disease. All aspects of epilepsy are explored through these cases, from the sometimes confusing initial diagnosis to patient responses and treatment methods. In this best-selling short text, the author also presents the lessons learned from these extraordinary cases. 110 Puzzling Cases in Epilepsy is useful for medical students, residents and all health care practitioners, as the practices used to understand these cases can be applied to other diagnoses as well.

Written by experts on the forefront of investigations of brain function, vision, and perception, the material presented is of an unparalleled scientific quality, and shows that analyses of enormous breadth and sophistication are required to probe the structure and function of brain regions. The articles are highly persuasive in showing what can be achieved by carrying out careful and imaginative experiments. "The Cat Primary Visual Cortex" should emerge as essential reading for all those interested in cerebral cortical processing of visual signals or researching or working in any field of vision. Key features include: comprehensive account of cat primary visual cortex; generous use of illustrations including color; coverage of research from structure to connections to functions; chapters by leaders in the field; and, topics presented on multiple, compatible levels.

Recent years have seen major advances in the understanding of motor and non-motor operations of the cerebellum, including its role in cognition, and important discoveries in the genetics of the cerebellar ataxias. This is a comprehensive text on the cerebellum and its disorders. It ranges from embryology and basic neuroanatomy to a thorough survey of the sporadic and hereditary disorders of the cerebellum. Models of cerebellar function and clinical-pathophysiological correlations are thoroughly covered, and there is an extensive and authoritative review of recent advances in the genetics of cerebellar diseases. The chapters are written by the leading international authorities on the cerebellum, including many of those who made fundamental discoveries in the field. The first comprehensive text on the cerebellum to be published for many years, this book will be essential reading for a wide range of basic and clinical neuroscientists, neurologists and others studying or treating cerebellar disorders.

This book, edited by one of the most distinguished specialists in the field, provides a comprehensive update on the use of sonography for imaging of the cervical region. All of the new technical modalities are considered in depth, including high-definition gray scale, enhanced color Doppler, and ultrasound contrast agents. Detailed morphological descriptions of numerous pathological processes are provided, followed by thorough discussion of differential diagnostic problems. In addition to presenting the basic information indispensable for physicians dealing with this anatomic region (ENT specialists, endocrinologists, specialists in vascular disease), each chapter reviews the most recent imaging findings with which physicians using sonography should be familiar. The book is original in addressing the examination of a particular anatomic region using a first-line imaging technique. It will have wide appeal and will be of great value to readers.

This practical, brief guide to diagnosing and treating causes of disorders of smell and taste is the only accessible handbook available for non-experts. Signs of problems with these two senses may be ignored by the patient or downplayed by the physician, but the disruption of the senses may be a first sign of serious illness. The wide range of conditions responsible for disorders of smell and taste make it difficult to determine the single underlying cause and to decide upon the best possible plan of treatment. "Disorders of Smell and Taste" will help physicians manage some of these patients thereby minimizing references to specialists.

Thoroughly revised and updated for its Second Edition, this atlas remains a must-have reference for anyone performing or interpreting EEGs in adults. This new edition shows readers how to maximize the usefulness of digital EEG. Coverage of subdural EEG and EEG in the intensive care unit has been expanded. The book contains more than 500 clear, easy-to-read EEG samples depicting artifacts, normal phenomena, epileptiform abnormalities, nonepileptiform abnormalities, and EEG patterns associated with impaired consciousness. Detailed legends explain the distinguishing features and clinical significance of each pattern.

"Atlas of Ambulatory EEG" is a first-of-its-kind publication in clinical neurophysiology, an atlas that comprehensively depicts normal, abnormal, and artifactual findings from actual ambulatory EEG recordings in a convenient and easily accessible format. As the use of ambulatory EEG has increased in recent years, the need for a concise atlas of ambulatory EEG has grown significantly, since ambulatory EEG tracings are subject to their own unique issues and artifacts, often not discussed in standard EEG atlases.This book begins with several chapters that introduce the history, technology, and clinical utility of ambulatory EEG. The bulk of the atlas consists of a page-by-page display of high-quality ambulatory EEG excerpts that are easy to review and come with short annotations describing the relevant findings."Atlas of Ambulatory EEG" is a critical resource for anyone involved in the interpretation of ambulatory EEG studies. It is a handy reference describing EEG patterns in normal and abnormal subjects based upon continuous monitoring techniques from widely used ambulatory EEG equipment. A section of EEG patterns without accompanying explanation will test the reader's ability to interpret the waveforms and answers will be given in a separate section. It includes an unique accompanying CD, which provides a sample of EEG files. The files have been provided by Digitrace - a company which maintains a vast library of EEG files. It has Internationally renowned contributors in the field. It is suitable for a wide audience including researchers in neurophysiology and neuroscience, as well as neurologists.

This book aims to cover the role of neurotransmitters, the substances released form neurons to act on neurons. It covers what they do, how they do it and how their activity is involved in brain function and affected by drugs and disease. The contents include: An overview of neurotransmitter function including their release, effects on neuronal excitability and receptor interaction Detailed description of the synaptic physiology, pharmacology and possible brain function of each neurotransmitter with particular emphasis on acetylcholine, glutamate, GABA, noradrenaline, dopamine, 5 hydroxytryptamine and the peptides, purines, histamine, steroids and nitric oxide An evaluation on how the different neurotransmitters may be involved in the initiation and maintenance of certain brain disorders such as Parkinson's disease, epilepsy, schizophrenia, depression, anxiety and dementia A review of neurotransmitters in sleep and consciousness and in the social problems of drugs and abuse Neurotransmitters, Drugs and Brain Function provides insights that will prove invaluable to students and researchers involved in pharmacology, neuroscience, medicine and psychology.

The leading reference book in the field of electrodiagnostic medicine just got better with this remarkable new edition, which is thoroughly revised and updated. Written by three of the leading authorities in the field along with several expert contributors, this comprehensive textbook continues to provide the fundamentals as well as the practical, clinical applications of electrodiagnostic medicine for novices and experienced practitioners alike.