Neurologia

Based on the XIVth International Congress on Parkinson's Disease, this volume provides a comprehensive account of the state of the art in the study and treatment of Parkinson's disease and related disorders. The book reviews the latest advances in all aspects of research and patient care, including neurobiology, genetics, epidemiology, PET and SPECT imaging, pharmacotherapy, surgical treatment, and management of comorbid and related conditions. Coverage of this title includes current recommendations for medical treatment of early and advanced Parkinson's disease, a detailed assessment of the benefits of deep brain stimulation, and guidelines for management of sleep disorders, depression, psychosis, and dementia in Parkinson's disease.

This book will help the general physician to recognize, diagnose and manage the common neurological problems in partnership with the neurologist. Written by an English general practitioner and two American neurologists, it is meant not only to span the gap between generalist and specialist but also to provide a standard of care that can be applied on both sides of the Atlantic in an increasingly global medical community.

The authors of the first edition worked together again to revise data for the second edition of this popular volume. Based at three of the world's leading centers for the study and treatment of headache, these experts share their insights on every aspect of this common and irritating condition. In particular, the sections on migraine, cluster headache and vascular disease have been updated. Based on the classification system developed by the International Headache Society, Headache in Clinical Practice provides those interested in headache with an up-to-date compendium of current opinion, from epidemiology, pathophysiology and investigation, through options for intervention and management.

The authors have compiled into a practical text their experiences encompassing over 20 years of work with patients in a persistent vegetative state. In addition to the partial or complete recovery of mental and neurological functions, another condition has been gaining in recognition in recent years: the state of minimal responder, which they elucidate in their book. This title bridges a gap in the specialized literature by providing neurologists, emergency physicians, physiatrists and internists, as well as therapists with new working tools. Also discussed are the relationship of the care-giving physician with the patient's family, and the planning and operating of units specialized in the treatment of patients in the persistent vegetative state.

Some of the most fascinating deficits in neuropsychology concern the failure to recognise common objects from one semantic category, such as living things, when there is no such difficulty with objects from another, such as non-living things. Over the past twenty years, numerous cases of these 'category specific' recognition and naming problems have been documented and several competing theories have been developed to account for the patients' disorders. Category Specificity in Brain and Mind draws together the neuropsychological literature on category-specific impairments, with research on how children develop knowledge about different categories, functional brain imaging work and computational models of object recognition and semantic memory. The chapters are written by internationally leading psychologists and neuroscientists and the result is a review of the most up-to-date thinking on how knowledge about different categories is acquired and organized in the mind, and where it is represented in the human brain. The text will be essential reading for advanced undergraduates and researchers in the field of category specificity and a rich source of information for neuropsychologists, experimental and developmental psychologists, cognitive scientists and philosophers.

This volume of "International Review of Neurobiology" defines primary biochemical causation of diabetic complications, identifies cellular glucose transducers, balancing roles of protein kinase C and MAP kinases, and sets in context the role of apoptosis and the interactive roles of neurons and Schwann cells. It also defines the cell biology of autonomic neuropathy, considers the balanced needs of science, clinical practice, and economics in clinical trial design, provides the definitive evaluation of aldose reductase inhibitors, and explains the failure of nerve growth factor. One of the most successful series in the field of neuroscience continues its standard of excellence with this newest edition. Published since 1959, "International Review of Neurobiology" is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists.

How do people with brain damage communicate? How does the partial or total loss of the ability to speak and use language fluently manifest itself in actual conversation? How are people with brain damage able to expand their cognitive ability through interaction with others - and how do these discursive activities in turn influence cognition? This groundbreaking collection of new articles examines the ways in which aphasia and other neurological deficits lead to language impairments that shape the production, reception and processing of language. Edited by noted linguistic anthropologist Charles Goodwin and with contributions from a wide range of international scholars, the articles provide a pragmatic and interactive perspective on the types of challenges that face aphasic speakers in any given act of communication. Conversation and Brain Damage will be invaluable to linguists, discourse analysts, linguistic and medical anthropologists, speech therapists, neurologists, psychiatrists, psychologists, workers in mental health care and in public health, sociologists, and readers interested in the long-term implications of brain damage.

This volume of the "International Review of Neurobiology" was written to assist researchers without any previous experience with in situ hybridization, allowing them to follow the protocols and expect good results. It contains all the information required for newcomers to achieve successful in situ hybridization results, and methods for improving the technique of those already utilizing it. Published since 1959, "International Review of Neurobiology" is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. Published since 1959, "International Review of Neurobiology" is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

"Motor Neuron Disease" is a state-of-the art monograph designed for the clinician who wants to stay on the cutting edge of the scientific understanding of motor neuron disease. The three most common motor neuron diseases are covered, namely sporadic amyotrophic lateral sclerosis, familial amyotrophic lateral sclerosis and childhood spinal muscular atrophy. Succinct, well-referenced and supported by appropriate illustrations the scope of the book includes current accepted diagnostic criteria for ALS, including practical case histories to aid differential diagnosis. The most common theories of pathogenesis are examined, and the most up-to-date review of the genetic implications for familial ALS included. A chapter on treatment includes coverage of the latest anti-excitotoxic drugs, in addition, a chapter on both management and support of the patient from the MND team is included. The book concludes with a review of the current trials , drug development and regulatory oversight and a look to the future and what therapies may be available in years to come. This book will appeal to neurologists and all those involved in the treatment and management of the patient with motor neuron disease as an easy to read review of current developments and trends in this challenging and fast moving field.

Evaluating the major strategies used to prevent stroke recurrence, such as antiplatelet and anticoagulant therapies, this reference assesses the efficacy of pharmacological interventions, therapeutic regimens, and quality of care for stroke patients - detecting risk factors and potential mechanisms of stroke to prevent functional disability and increase quality of life, independence, and psychological well-being in post-stroke management programs. It considers the complex issue of cost vs. benefit in post-stroke rehabilitation. Addressing common dysfunctions that occur after stroke, including motor impairment, neurobehavioral changes, cognitive loss, emotional disorders, and dementia, "Long-Term Effects of Stroke" discusses the patterns and epidemiology of ischemic and hemorrhagic stroke; the development of neurobiologically based therapeutic strategies; the possible emergence of depression, anxiety, mania, and psychosis; and; after stroke pharmacological and cell-based modalities to enhance stroke recovery. Offering perspectives from leading international authorities in the field, this book is a unique and valuable guide for clinical neurologists; cardiologists; cardiovascular specialists; cardiac, cardiovascular, and vascular surgeons; neurosurgeons; primary care, family practice, emergency room, and internal medicine physicians; physiologists; nurses, paramedical, and emergency medical personnel; and medical school students in these disciplines.

As minimally invasive surgery becomes the standard of care in neurosurgery, it is imperative that surgeons become skilled in the use of image-guided techniques. This outstanding new book provides an in-depth analysis of current and developing applications in this rapidly growing field. A highly acclaimed team of authors share their experience with this exciting technology, outlining benefits and limitations of each technique. The book begins with an overview of image-guided neurosurgery, and then continues with specific cranial and spinal procedures. You'll get full coverage of clinical applications for topics such as: videotactic neurosurgery, needle biopsy, cranial and spinal navigation, and much more! Key features of the book: * Full analysis of current and future applications of image-guided procedures * Detailed descriptions of procedures, from basic to the most advanced * An international "who's who" of contributors, all of whom have significantly advanced contributions to the field of image-guided surgery * Valuable information that leads to more effective results and optimal patient care Increasing evidence shows there are many advantages to using image-guided techniques. It can make procedures more efficient, minimize exposure and invasiveness, define resection boundaries, and optimize hardware placement. Here is the clinical reference that neurosurgeons, orthopaedic surgeons, and residents need to get the most up-to-date assessment of this vital field. Stay on the cutting-edge of an exciting new technology; order your copy of ADVANCED TECHNIQUES IN IMAGE-GUIDED BRAIN AND SPINE SURGERY today!

"Rapid Reference to Migraine" will provide the reader with authoritative and accessible information from a clinical expert in the field, to assist with treatment decisions. Each title in the "Rapid Reference" series covers diagnosis, prevention, treatment and management of the disease area. They also contain drug listings, clinical trial information, future developments, FAQs and website listings to keep the reader up to date with the disease area. With patients becoming better informed about the nature and management of their conditions, "Rapid Reference" is a timely new series that offers doctors easy access to the best information for patient care and management.

The thoroughly revised, updated Fifth Edition of this classic is the most comprehensive, current, and authoritative reference on all anticonvulsants available today. This edition features detailed profiles of newer drugs - including levetiracetam, oxcarbazepine, tiagabine, topiramate, and zonisamide - and new chapters on use of antiepileptic drugs in children and during pregnancy. Drugs are covered in alphabetical order and in an easy-to-follow format: mechanisms of action; chemistry, biotransformation, and pharmacokinetics; interactions; clinical efficacy and use; and, adverse effects. Coverage of clinical use includes nonepileptic and psychiatric disorders where appropriate. This edition has been trimmed to manageable size by shortening chapters on older, less frequently used drugs.

Clearly written, practical and well illustrated with drawings and photographs, including thermograms in the colour section, this new edition is a comprehensive clinical resource. New material has been added on differential diagnosis, causes, electrodiagnosis, feasibility of alternative therapies, and certain controversies.